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Mouse Pancreatic Lipase(PL)ELISA Kit

  • 中文名称:
    小鼠胰脂肪酶(PL)酶联免疫试剂盒
  • 货号:
    CSB-E16930m
  • 规格:
    96T/48T
  • 价格:
    ¥3600/¥2500
  • 其他:

产品详情

  • 产品描述:
    小鼠胰脂肪酶(PL)酶联免疫试剂盒(CSB-E16930m)为双抗夹心法ELISA试剂盒,定量检测血清、血浆、组织匀浆样本中的PL含量。小鼠胰脂肪酶(PL)是胰腺分泌的一种消化酶,参与脂肪的消化和吸收。其表达与肥胖等代谢性疾病密切相关,成为研究肥胖和代谢性疾病机制的重要靶点。通过研究PL的功能和调控,有助于开发治疗肥胖和相关代谢性疾病的药物。试剂盒检测范围为62.5 mU/mL-4000 mU/mL,适用于科研场景中评估小鼠模型胰腺外分泌功能、脂质代谢异常机制研究,或用于营养学、肥胖症及药物干预实验中胰脂肪酶动态变化的监测本品仅用于科研,不用于临床诊断,产品具体参数及操作步骤详见产品说明书。
  • 别名:
    PnlipPancreatic triacylglycerol lipase ELISA Kit; PL ELISA Kit; PTL ELISA Kit; Pancreatic lipase ELISA Kit; EC 3.1.1.3 ELISA Kit
  • 缩写:
    PL
  • Uniprot No.:
  • 种属:
    Mus musculus (Mouse)
  • 样本类型:
    serum, plasma, tissue homogenates
  • 检测范围:
    62.5 mU/mL-4000 mU/mL
  • 灵敏度:
    15.6 mU/mL
  • 反应时间:
    1-5h
  • 样本体积:
    50-100ul
  • 检测波长:
    450 nm
  • 研究领域:
    Metabolism
  • 测定原理:
    quantitative
  • 测定方法:
    Sandwich
  • 数据处理:
  • 货期:
    3-5 working days

产品评价

靶点详情

  • 功能:
    Plays an important role in fat metabolism. It preferentially splits the esters of long-chain fatty acids at positions 1 and 3, producing mainly 2-monoacylglycerol and free fatty acids, and shows considerably higher activity against insoluble emulsified substrates than against soluble ones.
  • 基因功能参考文献:
    1. the ability to degrade unfolded protein decreases in the aging pancreas, and this leads to reduction of pancreatic lipase activity and a decrease in lipid absorption PMID: 25033985
    2. pancreatic triglyceride lipase has a critical role in dietary cholesterol absorption and a minimal role in dietary fat absorption in mice PMID: 12915407
    3. PTL and CEL serve complementary functions, working together to mediate the absorption of a major portion of dietary fat and fat-soluble vitamin esters PMID: 17604277
  • 亚细胞定位:
    Secreted.
  • 蛋白家族:
    AB hydrolase superfamily, Lipase family
  • 组织特异性:
    Pancreas.
  • 数据库链接: