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中文名称:小鼠胰脂肪酶(PL)酶联免疫试剂盒
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货号:CSB-E16930m
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规格:96T/48T
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价格:¥3600/¥2500
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其他:
产品详情
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产品描述:小鼠胰脂肪酶(PL)酶联免疫试剂盒(CSB-E16930m)为双抗夹心法ELISA试剂盒,定量检测血清、血浆、组织匀浆样本中的PL含量。小鼠胰脂肪酶(PL)是胰腺分泌的一种消化酶,参与脂肪的消化和吸收。其表达与肥胖等代谢性疾病密切相关,成为研究肥胖和代谢性疾病机制的重要靶点。通过研究PL的功能和调控,有助于开发治疗肥胖和相关代谢性疾病的药物。试剂盒检测范围为62.5 mU/mL-4000 mU/mL,适用于科研场景中评估小鼠模型胰腺外分泌功能、脂质代谢异常机制研究,或用于营养学、肥胖症及药物干预实验中胰脂肪酶动态变化的监测本品仅用于科研,不用于临床诊断,产品具体参数及操作步骤详见产品说明书。
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别名:PnlipPancreatic triacylglycerol lipase ELISA Kit; PL ELISA Kit; PTL ELISA Kit; Pancreatic lipase ELISA Kit; EC 3.1.1.3 ELISA Kit
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缩写:PL
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Uniprot No.:
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种属:Mus musculus (Mouse)
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样本类型:serum, plasma, tissue homogenates
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检测范围:62.5 mU/mL-4000 mU/mL
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灵敏度:15.6 mU/mL
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反应时间:1-5h
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样本体积:50-100ul
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检测波长:450 nm
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研究领域:Metabolism
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测定原理:quantitative
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测定方法:Sandwich
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数据处理:
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货期:3-5 working days
引用文献
- Qingjie Huagong decoction inhibits pancreatic acinar cell pyroptosis by regulating circHipk3/miR-193a-5p/NLRP3 pathway MC Feng,Phytomedicine,2024
- Testosterone Promotes the Intestinal Replication and Dissemination of Coxsackievirus B3 in an Oral Inoculation Mouse Model AH Dhalech,Journal of virology,2023
- Cashew (Anacardium occidentale L.) Nuts Modulate the Nrf2 and NLRP3 Pathways in Pancreas and Lung after Induction of Acute Pancreatitis by Cerulein M Cordaro,Antioxidants,2020
- Undercarboxylated osteocalcin downregulates pancreatic lipase expression in an ATF4-dependent manner in pancreatic acinar cells Danbi Park,Bone,2019
相关产品
靶点详情
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功能:Plays an important role in fat metabolism. It preferentially splits the esters of long-chain fatty acids at positions 1 and 3, producing mainly 2-monoacylglycerol and free fatty acids, and shows considerably higher activity against insoluble emulsified substrates than against soluble ones.
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基因功能参考文献:
- the ability to degrade unfolded protein decreases in the aging pancreas, and this leads to reduction of pancreatic lipase activity and a decrease in lipid absorption PMID: 25033985
- pancreatic triglyceride lipase has a critical role in dietary cholesterol absorption and a minimal role in dietary fat absorption in mice PMID: 12915407
- PTL and CEL serve complementary functions, working together to mediate the absorption of a major portion of dietary fat and fat-soluble vitamin esters PMID: 17604277
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亚细胞定位:Secreted.
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蛋白家族:AB hydrolase superfamily, Lipase family
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组织特异性:Pancreas.
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数据库链接:
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