Mouse Complement C2(C2) ELISA kit
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中文名称:小鼠补体C2(C2)酶联免疫试剂盒
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货号:CSB-EL003658MO
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规格:96T/48T
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价格:¥3600/¥2500
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其他:
产品详情
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产品描述:CUSABIO小鼠补体C2(C2)酶联免疫试剂盒(货号CSB-EL003658MO),基于竞争性酶联免疫吸附法(ELISA)原理开发,适用于定量检测小鼠血清、血浆及组织匀浆样本中的补体C2蛋白浓度。补体C2是补体系统经典途径和凝集素途径的关键成分,参与C3转化酶的形成,在免疫防御和炎症反应中发挥重要作用,其表达水平与免疫调节、感染性疾病及自身免疫机制研究密切相关。本试剂盒检测范围为18.75-300 ng/mL,通过预包被特异性抗体实现目标蛋白的高灵敏度捕获,结合酶标二抗与底物显色系统完成定量分析。该产品可广泛应用于基础免疫学研究,支持小鼠模型中补体系统功能分析、炎症相关疾病机制探索、药物干预效果评估等科研场景,尤其适用于通过血清或组织样本动态监测补体C2在病理生理过程中的表达变化。实验操作兼容常规实验室设备,提供标准品及配套试剂,确保实验数据的可靠性和重复性。本产品仅限科学研究使用。
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别名:C2Complement C2 ELISA Kit; EC 3.4.21.43 ELISA Kit; C3/C5 convertase) [Cleaved into: Complement C2b fragment; Complement C2a fragment] ELISA Kit
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缩写:
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Uniprot No.:
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种属:Mus musculus (Mouse)
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样本类型:serum, plasma, tissue homogenates
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检测范围:18.75 ng/mL-300 ng/mL
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灵敏度:18.75 ng/mL
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反应时间:1-5h
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样本体积:50-100ul
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检测波长:450 nm
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研究领域:Immunology
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测定原理:quantitative
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测定方法:Competitive
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数据处理:
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货期:3-5 working days
相关产品
靶点详情
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功能:Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.
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基因功能参考文献:
- Data indicate that activation of C5 in experimental cerebral malaria likely occurs via coagulation enzymes of the extrinsic protease pathway. PMID: 22689574
- The more pronounced lack of complement activation in Bf/C2-/- mice leads to uncontrolled infection due to an opsonophagocytic defect PMID: 18672286
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亚细胞定位:Secreted.
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蛋白家族:Peptidase S1 family
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数据库链接:
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