Monkey Interleukin-8,IL-8 ELISA Kit

产品详情

产品描述：

CUSABIO猴子白介素8（IL-8/CXCL8）酶联免疫检测试剂盒（货号CSB-E08051Mo），采用双抗体夹心法实现定量检测，适用于分析血清、血浆、细胞培养上清液及组织匀浆中的IL-8含量，其检测灵敏度覆盖31.25-2000 pg/mL的宽泛线性范围。IL-8作为重要的CXC趋化因子家族成员，在介导中性粒细胞趋化、血管生成及炎症反应调控中发挥核心作用，常作为炎症性疾病和免疫调控研究的生物标志物。本试剂盒通过特异性捕获抗体和检测抗体的组合，实现对目标蛋白的高效识别，支持科研人员精确量化不同实验条件下IL-8的表达水平变化。在基础研究领域，该产品可应用于灵长类动物模型中的感染性疾病机制探索、炎症相关信号通路研究，以及抗炎药物或免疫调节剂的体外筛选实验。实验过程中需注意样本预处理规范，避免反复冻融对检测结果产生影响。
别名：

CXCL8 ELISA kit; IL8Interleukin-8 ELISA kit; IL-8 ELISA kit; C-X-C motif chemokine 8 ELISA kit; Chemokine ELISA kit; C-X-C motif) ligand 8 ELISA kit
缩写：

CXCL8
Uniprot No.：

P67813
种属：

Monkey
样本类型：

serum, plasma, cell culture supernates, tissue homogenates
检测范围：

31.25 pg/mL-2000 pg/mL
灵敏度：

7.81 pg/mL
反应时间：

1-5h
样本体积：

50-100ul
检测波长：

450 nm
研究领域：

Immunology
测定原理：

quantitative
测定方法：

Sandwich

精密度：

Intra-assay Precision (Precision within an assay): CV%<8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV%<10%
Three samples of known concentration were tested in twenty assays to assess.

标准曲线：

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

功能：

IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus.
基因功能参考文献：
1. Stress decreased IL-8 gene expression in both CeA lesioned and non-lesioned animals. But, CeA lesions increased the tissue expression of IL-8 mRNA prior to and after stress exposure. PMID: 16574374
亚细胞定位：

Secreted.
蛋白家族：

Intercrine alpha (chemokine CxC) family
数据库链接：

KEGG: mcc:613028

STRING: 9544.ENSMMUP00000005115

UniGene: Mmu.3363