Monkey Interleukin-1 alpha (IL1A) ELISA kit

产品详情

Intra-assay Precision (Precision within an assay): CV%<8%

Three samples of known concentration were tested twenty times on one plate to assess.

Inter-assay Precision (Precision between assays): CV%<10%

Three samples of known concentration were tested in twenty assays to assess.

产品描述：

CUSABIO猴白介素1a（IL1A）酶联免疫试剂盒（货号：CSB-E10041Mo），采用双抗体夹心法原理实现定量检测，适用于血清、血浆及组织匀浆样本中IL1A蛋白的科研分析。IL1A是一种重要的促炎细胞因子，参与先天免疫应答调控，在炎症反应、细胞增殖及组织修复等过程中发挥关键作用，其表达水平变化常与感染、自身免疫性疾病或应激反应相关。试剂盒检测灵敏度为7.8 pg/mL，线性范围为7.8-500 pg/mL，可精准捕获低浓度目标蛋白，满足不同样本基质的需求。实验流程基于预包被特异性抗体的微孔板，通过标准品与样本中IL1A的竞争性结合，结合酶标二抗显色反应实现定量分析，适用于探索灵长类动物模型中IL1A的生物学功能、炎症相关疾病机制研究，或评估药物干预、基因修饰对IL-1信号通路的影响，为免疫学、病理学及药理学领域的体外实验提供可靠工具。
别名：

IL1A ELISA Kit; Interleukin-1 alpha ELISA Kit; IL-1 alpha ELISA Kit; Hematopoietin-1 ELISA Kit
缩写：

IL1A
Uniprot No.：

P48089
种属：

Monkey
样本类型：

serum, plasma, tissue homogenates
检测范围：

7.8 pg/mL-500 pg/mL
灵敏度：

1.95 pg/mL
反应时间：

1-5h
样本体积：

50-100ul
检测波长：

450 nm
研究领域：

Immunology
测定原理：

quantitative
测定方法：

Sandwich

精密度：

标准曲线：

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

功能：

Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
亚细胞定位：

Cytoplasm. Secreted.
蛋白家族：

IL-1 family
数据库链接：

KEGG: mcc:700193

STRING: 9544.ENSMMUP00000026006

UniGene: Mmu.3361