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中文名称:人神经节苷脂(GM1)抗体(IgG)酶联免疫试剂盒
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货号:CSB-E09694h
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规格:96T/48T
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价格:¥3200/¥2500
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其他:
产品详情
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产品描述:CUSABIO人神经节苷脂(GM1)IgG抗体检测专用酶联免疫试剂盒(货号:CSB-E09694h),适用于血清样本中GM1抗体的定性分析。GM1作为神经细胞膜重要成分,其抗体水平异常与神经退行性疾病、自身免疫性神经病变等密切相关,在格林-巴利综合征和多发性硬化等疾病的病理机制研究中具有重要价值。CUSABIO试剂盒采用间接法检测原理,通过抗原预包被板捕获样本中的特异性抗体,结合酶标二抗显色系统实现目标抗体的定性检测,具有操作便捷、特异性强的特点。研究者可通过该产品探究GM1抗体在神经系统疾病模型中的表达规律,评估实验性治疗方案对自身免疫反应的调控作用,或在药物开发中作为潜在生物标志物的检测工具。具体检测范围可根据实验设计需求进一步确认,建议搭配标准品进行半定量分析。CUSABIO科研实验提供可靠的技术支持,广泛应用于基础医学、神经生物学及药理学研究领域。
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缩写:GM1 Ab (IgG)
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种属:Homo sapiens (Human)
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样本类型:serum
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检测范围:Request Information
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灵敏度:Request Information
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反应时间:1-5h
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样本体积:50-100ul
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检测波长:450 nm
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研究领域:Neuroscience
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测定原理:qualitative
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测定方法:Indirect
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精密度:
Intra-assay Precision (Precision within an assay): CV%<15%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV%<15%
Three samples of known concentration were tested in twenty assays to assess.
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标准曲线:
Test parameter
specification
test result
Positive control
>0.8
1.128
Negative control
<0.1
0.074
Positive rate
10,Positive
100%
Negative rate
10,Negative
100%
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货期:3-5 working days
引用文献
- Sialic Acid and Anti-ganglioside Antibody Levels in Children with Autism Spectrum Disorders Yang X.et al,Brain Res.,2017
- Analysis of serum interleukin-27 and interleukin-35 concentrations in patients with Guillain-Barré syndrome Zhang LJ.et al,Clin Chim Acta.,2017
- Reduced soluble RAGE is associated with disease severity of axonal Guillain-Barr茅 syndrome. Zhang DQ.et al,Sci Rep.,2016
相关问答
I would like to know the specificty of this kit, does the kit detect anti-sialylated GM1 autoantibody or anti-asialo-GM1 autoantibody or both?
GM1 (monosialotetrahexosylganglioside) the "prototype" ganglioside, is a member of the ganglio series of gangliosides which contain one sialic acid residue.
We have no such detailed types for anti-sialylated GM1 autoantibody or anti-asialo-GM1 autoantibody.
As for this kit CSB-E09694h, it detects GM1 Ab (IgG).
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