Human Threonyl-tRNA synthetase, cytoplasmic(TARS) ELISA kit

产品详情

产品描述：

人苏氨酰-tRNA合成酶,细胞质(TARS)酶联免疫试剂盒（CSB-EL023131HU）为双抗夹心法ELISA试剂盒，定量检测组织匀浆、细胞裂解物.样本中的TARS含量。试剂盒检测范围为0.156ng/ml- 10 ng/ml，适用于探索TARS在基础科研中的表达调控机制，如在肿瘤细胞蛋白质合成研究、代谢性疾病模型构建或基因表达调控实验中评估酶活性变化，支持细胞生物学、分子机制研究等领域的定量分析需求。本品仅用于科研，不用于临床诊断，产品具体参数及操作步骤详见产品说明书。
别名：

cytoplasmic ELISA Kit; MGC9344 ELISA Kit; SYTC_HUMAN ELISA Kit; TARS ELISA Kit; Threonine tRNA ligase 1 ELISA Kit; Threonine tRNA ligase 1; cytoplasmic ELISA Kit; Threonine--tRNA ligase ELISA Kit; Threonyl tRNA synthetase ELISA Kit; Threonyl tRNA synthetase; cytoplasmic ELISA Kit; Threonyl-tRNA synthetase ELISA Kit; ThrRS ELISA Kit
缩写：

TARS
Uniprot No.：

P26639
种属：

Homo sapiens (Human)
样本类型：

tissue homogenates, cell lysates.
检测范围：

0.156ng/ml- 10 ng/ml
灵敏度：

0.039 ng/ml
反应时间：

1-5h
样本体积：

50-100ul
检测波长：

450 nm
研究领域：

Metabolism
测定原理：

quantitative
测定方法：

Sandwich
线性度：
数据处理：

ELISA操作视频及标曲绘制软件下载
货期：

3-5 working days

功能：

Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged tRNA(Thr) via its editing domain, at the post-transfer stage.
基因功能参考文献：
1. Results show that TARS expression is increased in epithelial ovarian cancer. PMID: 25163878
2. Our series mainly underscores that interstitial lung disease is frequent in anti-PL7(tars antibody)patients, leading to high morbidity. PMID: 23375620
3. A previously undiscovered function for TARS as an angiogenic, pro-migratory extracellular signaling molecule. PMID: 23425968
亚细胞定位：

Cytoplasm.
蛋白家族：

Class-II aminoacyl-tRNA synthetase family
数据库链接：

HGNC: 11572

OMIM: 187790

KEGG: hsa:6897

STRING: 9606.ENSP00000265112

UniGene: Hs.481860