Human Myeloid-derived growth factor(MYDGF) ELISA kit
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中文名称：人骨髓衍生生长因子 (MYDGF)酶联免疫试剂盒
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货号：CSB-EL003433HU
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规格：96T/48T
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价格：￥3600/￥2500
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其他：
产品详情
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产品描述：人骨髓衍生生长因子 (MYDGF)酶联免疫试剂盒（CSB-EL003433HU）为双抗夹心法ELISA试剂盒，定量检测血清、血浆、组织匀浆样本中的MYDGF含量。MYDGF 即中脑星形胶质细胞衍生神经营养因子，一般在心脏中发挥调控能量代谢、保护心肌等作用。试剂盒检测范围为0.156 ng/mL-10 ng/mL，适用于心血管疾病机制研究、代谢调控通路探索、抗炎药物开发等科研场景中生物标志物表达水平的动态监测，亦可用于评估疾病模型动物或细胞实验中MYDGF的调控效果。本品仅用于科研，不用于临床诊断，产品具体参数及操作步骤详见产品说明书。
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别名：C19orf10 ELISA Kit; Chromosome 19 open reading frame 10 ELISA Kit; CS010_HUMAN ELISA Kit; EUROIMAGE1875335 ELISA Kit; IL 25 ELISA Kit; IL 27 ELISA Kit; IL-25 ELISA Kit; IL25 ELISA Kit; IL27 ELISA Kit; IL27w ELISA Kit; Interleukin 25 ELISA Kit; Interleukin 27 working designation ELISA Kit; Interleukin-25 ELISA Kit; Interleukin25 ELISA Kit; R33729 1 ELISA Kit; R337291 ELISA Kit; SF20 ELISA Kit; Stromal cell derived growth factor ELISA Kit; Stromal cell derived growth factor SF20 ELISA Kit; Stromal cell-derived growth factor SF20 ELISA Kit; Uncharacterized protein C19orf10 precursor ELISA Kit; UPF0556 protein C19orf10 ELISA Kit
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Uniprot No.：
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种属：Homo sapiens (Human)
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样本类型：serum, plasma, tissue homogenates
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检测范围：0.156 ng/mL-10 ng/mL
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灵敏度：0.039 ng/mL
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反应时间：1-5h
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样本体积：50-100ul
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检测波长：450 nm
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研究领域：Cardiovascular
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货期：3-5 working days
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靶点详情
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功能：Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway. Involved in endothelial cell proliferation and angiogenesis.
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基因功能参考文献：
- Bone marrow-derived monocytes and macrophages produce this protein endogenously to protect and repair the heart after myocardial infarction. PMID: 25581518
- Taken together, these data suggest that c19orf10 might be one of the growth factors and potential molecular targets activated in HCC. PMID: 21128247
- we identified a novel protein, c19orf10 (chromosome 19 open reading frame 10), produced by fibroblast-like synoviocytes PMID: 17362502
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亚细胞定位：Secreted. Endoplasmic reticulum-Golgi intermediate compartment. Endoplasmic reticulum. Golgi apparatus.
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蛋白家族：MYDGF family
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组织特异性：Expressed in eosinophils (at protein level). Expressed in bone marrow cells. Expressed in synovial tissue. Found in synovial fluid of patients with arthropaties.
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数据库链接：
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