Human Leucine-rich repeat LGI family member 3(LGI3) ELISA kit
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中文名称：人富亮氨酸重复LGI家族成员3(LGI3)酶联免疫试剂盒
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货号：CSB-EL012900HU
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规格：96T/48T
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价格：￥3600/￥2500
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其他：
产品详情
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产品描述：人富亮氨酸重复LGI家族成员3(LGI3)酶联免疫试剂盒（CSB-EL012900HU）为双抗夹心法ELISA试剂盒，定量检测血清、血浆,组织匀浆样本中的LGI3含量。LGI3是一种神经发育基因，其表达异常与自闭症等神经精神疾病相关。研究显示，LGI3通过调节神经元间的突触传递，影响神经递质释放，进而影响大脑功能。其研究机制涉及基因表达调控、突触可塑性及神经环路功能等多个层面。试剂盒检测范围为0.156 ng/mL-10 ng/mL，支持研究人员开展神经生物学基础研究、疾病机制探索等实验，例如通过检测不同处理条件下细胞模型、动物实验样本中LGI3的表达动态变化，或结合其他分子标记物进行神经退行性疾病的关联性研究本品仅用于科研，不用于临床诊断，产品具体参数及操作步骤详见产品说明书。
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别名：Leucine rich repeat LGI family member 3 ELISA Kit; Leucine-rich glioma inactivated protein 3 ELISA Kit; Leucine-rich glioma-inactivated protein 3 ELISA Kit; Leucine-rich repeat LGI family member 3 ELISA Kit; LGI1 like protein 4 ELISA Kit; LGI1-like protein 4 ELISA Kit; LGI3 ELISA Kit; LGI3_HUMAN ELISA Kit; LGIL4 ELISA Kit
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缩写：LGI3
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Uniprot No.：
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种属：Homo sapiens (Human)
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样本类型：serum, plasma,tissue homogenates
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检测范围：0.156 ng/mL-10 ng/mL
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灵敏度：0.039 ng/mL
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反应时间：1-5h
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样本体积：50-100ul
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检测波长：450 nm
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研究领域：Neuroscience
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测定原理：quantitative
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测定方法：Sandwich
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数据处理：
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货期：3-5 working days
产品评价
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靶点详情
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功能：May participate in the regulation of neuronal exocytosis.
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基因功能参考文献：
- The expression of LGI3 was significantly associated with the prognosis of brain, colorectal and lung cancer. PMID: 29257304
- Leucine-rich glioma inactivated 3 is a cytokine in human skin that promotes melanin production. PMID: 24903553
- LGI3 was mostly expressed in the granular layer of the epidermis of human skin. PMID: 23815230
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亚细胞定位：Secreted. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Cell junction, synapse, synaptosome.
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组织特异性：Widely expressed, with highest levels in brain and lung.
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数据库链接：
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