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中文名称：人上皮细胞粘附分子(EPCAM)酶联免疫试剂盒
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货号：CSB-EL007717HU
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规格：96T/48T
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价格：￥3600/￥2500
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其他：
产品详情
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产品描述：CUSABIO人上皮细胞粘附分子（EPCAM）酶联免疫检测试剂盒（货号：CSB-EL007717HU），采用双抗体夹心法定量检测血清、血浆、组织匀浆及细胞裂解液等样本中EPCAM蛋白的含量，检测灵敏度达0.625 ng/ml，线性范围为0.625-40 ng/ml。EPCAM是一种跨膜糖蛋白，广泛表达于正常上皮细胞及多种肿瘤细胞表面，参与细胞间粘附、增殖及干细胞维持等生物学过程，其异常表达与肿瘤转移、预后评估及靶向治疗研究密切相关。本试剂盒通过特异性捕获抗体固定样本中的EPCAM抗原，并利用标记抗体与底物显色系统实现定量分析，适用于肿瘤生物学研究、上皮细胞功能探索、药物作用机制分析等科研领域，为体外实验提供高特异性的检测工具。实验操作兼容常规酶标仪检测，能够满足基础研究中对EPCAM蛋白水平的精准定量需求。
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别名：EPCAM ELISA kit; TACSTD1Epithelial cell adhesion molecule ELISA kit; Ep-CAM ELISA kit; Tumor-associated calcium signal transducer 1 ELISA kit; CD antigen CD326 ELISA kit
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缩写：
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Uniprot No.：
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种属：Homo sapiens (Human)
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样本类型：serum, plasma, tissue homogenates, cell lysates.
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检测范围：0.625 ng/ml-40 ng/ml
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灵敏度：0.156 ng/ml
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反应时间：1-5h
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样本体积：50-100ul
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检测波长：450 nm
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研究领域：Tags & Cell Markers
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测定原理：quantitative
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测定方法：Sandwich
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数据处理：
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货期：3-5 working days
引用文献
- Correlation between membrane proteins and sizes of extracellular vesicles and particles: A potential signature for cancer diagnosis C Zhai,Journal of extracellular vesicles,2023
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靶点详情
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功能：May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.
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亚细胞定位：Lateral cell membrane; Single-pass type I membrane protein. Cell junction, tight junction.
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蛋白家族：EPCAM family
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数据库链接：
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