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中文名称：人Ⅱ型胶原交联C端肽(CTX-Ⅱ)酶联免疫试剂盒
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货号：CSB-E14328h
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规格：96T/48T
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价格：￥3600/￥2500
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其他：
产品详情
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产品描述：人Ⅱ型胶原交联C端肽(CTX-Ⅱ)酶联免疫试剂盒（CSB-E14328h）为双抗夹心法ELISA试剂盒，定量检测血清、血浆、尿液样本中的CTX-含量。靶点研究是药物研发的关键，涉及识别疾病相关分子或细胞结构，通过药物相互作用产生治疗效果。研究机制包括基因组学、蛋白质组学、生物信息学和高通量筛选技术，旨在发现新靶点，设计精准药物。CTX-320是一种基于CRISPR/Cas9技术的基因编辑药物，用于治疗代谢病、动脉粥样硬化和主动脉瓣狭窄。试剂盒检测范围为0.312 ng/mL-20 ng/mL，常用于研究关节代谢动态及软骨损伤机制；适用于体外研究关节疾病模型中的生物标志物表达、药物干预效果评估或病理机制探索；为软骨代谢研究及骨关节相关疾病的基础研究提供可靠工具本品仅用于科研，不用于临床诊断，产品具体参数及操作步骤详见产品说明书。
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别名：Cross Linked C-Telopeptide Of Type 2 Collagen ,CTX-2,_x000D_ Cross Linked C-Telopeptide Of Type II Collagen ,CTX-II
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缩写：CTX-
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种属：Homo sapiens (Human)
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样本类型：serum, plasma, urine
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检测范围：0.312 ng/mL-20 ng/mL
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灵敏度：0.078 ng/mL
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反应时间：1-5h
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样本体积：50-100ul
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检测波长：450 nm
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研究领域：Others
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测定原理：quantitative
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测定方法：Sandwich
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精密度：
Intra-assay Precision (Precision within an assay): CV%<8% Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV%<10% Three samples of known concentration were tested in twenty assays to assess. -
线性度：
To assess the linearity of the assay, samples were spiked with high concentrations of human CTX-Ⅱ in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay. Sample Serum(n=4) 1:1 Average % 93 Range % 86-98 1:2 Average % 100 Range % 96-104 1:4 Average % 99 Range % 92-105 1:8 Average % 92 Range % 87-98 -
回收率：
The recovery of human CTX-Ⅱ spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section. Sample Type Average % Recovery Range Serum (n=5) 96 90-100 EDTA plasma (n=4) 100 95-105 -
标准曲线：
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed. 
ng/ml OD1 OD2 Average Corrected 20 2.462 2.671 2.567 2.423 10 1.959 1.964 1.962 1.818 5 1.398 1.345 1.372 1.228 2.5 0.822 0.837 0.830 0.686 1.25 0.546 0.558 0.552 0.408 0.625 0.382 0.396 0.389 0.245 0.312 0.281 0.297 0.289 0.145 0 0.142 0.146 0.144 -
数据处理：
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货期：3-5 working days
引用文献
- Identification of plasma and urinary inflammatory markers in severe knee osteoarthritis: Relations with synovial fluid markers JS Shin,Knee surgery & related research,2024
- Micro-fragmented adipose tissue (mFAT) associated with arthroscopic debridement provides functional improvement in knee osteoarthritis: a randomized controlled trial M Ulivi,Knee surgery, sports traumatology, arthroscopy,2022
- Comparison of Extracorporeal Shockwave Therapy with Non-Steroid Anti-Inflammatory Drugs and Intra-Articular Hyaluronic Acid Injection for Early Osteoarthritis of the Knees SW Jhan,Biomedicines,2022
- The Effect of Atorvastatin in Knee Osteoarthritis EM Jasim,Indian Journal of Forensic Medicine & Toxicology,2021
- Elevated synovial fluid IL-33 and IL-6 levels and cartilage degeneration in stage III osteonecrosis of the femoral head Gao Y H, et al,Technology and Health Care,2019
- Plasma C-terminal cross-linking telopeptide of type II collagen as a biomarker in advanced stages of femoral head osteonecrosis MincongHe, et al,Biomedicine & Pharmacotherapy,2019
- A cross sectional study of bone and cartilage biomarkers: correlation with structural damage in rheumatoid arthritis Wael Ben Achour.et al,Libyan Journal of Medicine ?,2018
- Deer Bone Extract Supplementation for Mild-to-Moderate Knee Osteoarthritis Symptoms: A Randomized, Double-Blind, Placebo-Controlled Trial Shin D.et al,J Med Food,2018
- Randomized double-blind placebo-controlled study of the efficacy of Litsea japonica fruit extract in subjects with mild to moderate knee osteoarthritis Youngsook Ahn.et al,Journal of Functional Foods,2017
- Effect of Vitamin D on Peripheral Blood Mononuclear Cells from Patients with Psoriasis Vulgaris and Psoriatic Arthritis Cubillos S.et al,PLoS One.,2016
- Análise dos níveis séricos do biomarcador CTX┥I em atletas profissionais de futebol de sal Severino R M.et al,Revista Brasileira de Ortopedia,2015
- UM206, a selective Frizzled antagonist, attenuates adverse remodeling after myocardial infarction in swine Uitterdijk A. et al,Lab Invest,2015
- Analysis on the serum levels of the biomarker CTX-II in professional indoor soccer players over the course of one season Rodrigo Miziara Severino et al,Revista Brasileira de Ortopedia,2015
- The construction of three-dimensional micro-fluidic scaffolds of biodegradable polymers by solvent vapor based bonding of micro-molded layers. Ryu W. et al,Biomaterials,2007
- Alteration of Cartilage Degeneration and Inflammation Markers in Temporomandibular Joint Osteoarthritis Occurs Proportionally Vos LM et al,J Oral Maxillofac Surg,2013
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■ 常见问题解答
Q:
I want an citation/publication about Human Cross Linked C-Telopeptide Of Type II Collagen ,CTX-2 ELISA Kit CSB-E14328h in urine samples. Do you have any papers?
A:
Thanks for your inquiry.
This kit can be used to test urine samples.
We tested human normal urine samples before and the test value is 0.3--1.25ng/ml. Some customers said the detection rate is very low. I will send you the manual and published reference by e-mail to you soon.Pls let me know if you have any further questions. Thank you.
This kit can be used to test urine samples.
We tested human normal urine samples before and the test value is 0.3--1.25ng/ml. Some customers said the detection rate is very low. I will send you the manual and published reference by e-mail to you soon.Pls let me know if you have any further questions. Thank you.
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