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中文名称：人CC趋化因子4(CCL4)酶联免疫试剂盒
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货号：CSB-EL004797HU
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规格：96T/48T
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价格：￥3600/￥2500
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其他：
产品详情
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产品描述：人CC趋化因子4（CCL4）是趋化因子家族的重要成员，通过介导免疫细胞迁移参与炎症反应、感染防御及肿瘤微环境调控等生理病理过程，在免疫性疾病、感染性疾病及肿瘤机制研究中备受关注。本试剂盒（货号：CSB-EL004797HU）采用双抗体夹心法定量检测人血清、血浆或组织匀浆样本中的CCL4蛋白水平，灵敏度为31.2 pg/ml，检测范围横跨31.2-2000 pg/ml，可精准识别低浓度目标分子。该试剂盒经过严格验证，适用于多种生物样本类型，操作流程标准化，数据重复性良好。科研工作者可借助本产品定量分析CCL4在炎症模型中的表达动态，探究其在免疫细胞趋化、病原体感染后免疫应答或肿瘤相关巨噬细胞活化中的作用机制，为免疫调控研究、疾病模型构建及药物干预效果评估提供可靠工具。本产品仅限科学研究使用，不适用于医疗诊断或其他非科研场景。
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别名：MIP 1 beta ELISA Kit; Secreted protein G 26 ELISA Kit; ACT 2 ELISA Kit; ACT-2 ELISA Kit; ACT2 ELISA Kit; AT744.1 ELISA Kit; AT744.2 ELISA Kit; C C motif chemokine 4 ELISA Kit; C C motif chemokine 4 like ELISA Kit; C C motif chemokine ligand 4 like 1 ELISA Kit; C C motif chemokine ligand 4 like 2 ELISA Kit; CC chemokine ligand 4 ELISA Kit; CC chemokine ligand 4L1 ELISA Kit; CC chemokine ligand 4L1d2 ELISA Kit; CC chemokine ligand 4L2 ELISA Kit; CCL4 ELISA Kit; CCL4_HUMAN ELISA Kit; ccl4l 1 ELISA Kit; CCL4L ELISA Kit; CCL4L1 ELISA Kit; Chemokine (C C motif) ligand 4 ELISA Kit; Chemokine (C C motif) ligand 4 like 1 ELISA Kit; Chemokine (C C motif) ligand 4 like 1; telomeric ELISA Kit; Chemokine (C C motif) ligand 4 like 2 ELISA Kit; Chemokine CC Motif Ligand 4 ELISA Kit; G 26 ELISA Kit; G 26 T lymphocyte secreted protein ELISA Kit; G-26 T-lymphocyte-secreted protein ELISA Kit; HC21 ELISA Kit; Immune activation 2 ELISA Kit; LAG 1 ELISA Kit; LAG-1 ELISA Kit; LAG1 ELISA Kit; Lymphocyte activation gene 1 ELISA Kit; Lymphocyte activation gene 1 protein ELISA Kit; Macrophage inflammatory protein 1 beta ELISA Kit; Macrophage inflammatory protein 1-beta ELISA Kit; Macrophage inflammatory protein 1b2 ELISA Kit; MGC104418 ELISA Kit; MGC126025 ELISA Kit; MGC126026 ELISA Kit; MIP-1-beta ELISA Kit; MIP-1-beta(1-69) ELISA Kit; MIP-1-beta(3-69) ELISA Kit; MIP1 beta ELISA Kit; MIP1B ELISA Kit; MIP1B1 ELISA Kit; Monocyte adherence induced protein 5 alpha ELISA Kit; PAT 744 ELISA Kit; Protein H400 ELISA Kit; SCYA2 ELISA Kit; SCYA4 ELISA Kit; SCYA4L ELISA Kit; SCYA4L1 ELISA Kit; SCYA4L2 ELISA Kit; SCYQ4L2 ELISA Kit; Secreted protein G 26 ELISA Kit; Secreted protein G26 ELISA Kit; SIS gamma ELISA Kit; SIS-gamma ELISA Kit; Small inducible cytokine A4 (homologous to mouse Mip 1b) ELISA Kit; Small inducible cytokine A4 ELISA Kit; small inducible cytokine A4-like ELISA Kit; Small-inducible cytokine A4 ELISA Kit; T cell activation protein 2 ELISA Kit; T-cell activation protein 2 ELISA Kit
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缩写：
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Uniprot No.：
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种属：Homo sapiens (Human)
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样本类型：serum, plasma, tissue homogenates
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检测范围：31.2 pg/ml - 2000 pg/ml
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灵敏度：7.8 pg/ml
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反应时间：1-5h
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样本体积：50-100ul
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检测波长：450 nm
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研究领域：Immunology
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测定原理：quantitative
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测定方法：Sandwich
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数据处理：
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货期：3-5 working days
引用文献
- High and selective cytotoxicity of ex vivo expanded allogeneic human natural killer cells from peripheral blood against bladder cancer: implications for natural killer cell instillation after transurethral resection of bladder tumor CL Yeh,Journal of experimental & clinical cancer research,2024
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相关产品
靶点详情
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功能：Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.
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基因功能参考文献：
- identified 13 ADCC-activated genes. Six gene expression assays including 8 of the 13 genes (CCL3, CCL4/CCL4L1/CCL4L2, CD160, IFNG, NR4A3 and XCL1/XCL2) were analyzed in 127 kidney biopsies PMID: 25449536
- PCR results show that lower copy numbers of CCL4L1 are observed in the Caucasian population nd higher copy numbers are observed in the Black population of South Africa. PMID: 24727646
- CCL4L1 allele frequency is higher in severe psoriasis, whereas CCL4L2 is more frequent in patients with a milder disease. PMID: 21614014
- multiple copies of CCL3L1 and CCL4L1 present in a single diploid genome are the result of segmental duplication at chromosome 17q12 PMID: 15028295
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亚细胞定位：Secreted.
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蛋白家族：Intercrine beta (chemokine CC) family
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数据库链接：
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