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中文名称:人载脂蛋白A4(Apo-A4)酶联免疫试剂盒
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货号:CSB-E15088h
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规格:96T/48T
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价格:¥3600/¥2500
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其他:
产品详情
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产品描述:人载脂蛋白A4(Apo-A4)酶联免疫试剂盒(CSB-E15088h)为双抗夹心法ELISA试剂盒,定量检测血清、血浆、组织匀浆样本中的APOA4含量。APOA4 即载脂蛋白 A4,在脂质代谢等方面发挥重要作用。研究发现它能促进胆固醇逆向转运、调节脂蛋白代谢。其作为靶点,在治疗高脂血症、动脉粥样硬化等疾病上有潜在价值,通过调控相关代谢机制有望开发新型治疗方案。试剂盒检测范围为0.041 ng/ml- 30 ng/ml,灵敏度为0.041 ng/ml。适用于心血管疾病、脂代谢异常及相关病理机制的体外研究。可应用于基础科研中Apo - A4表达水平的动态监测,如动脉粥样硬化模型研究、肥胖或糖尿病相关代谢紊乱的分子机制探索,以及药物干预对脂蛋白代谢影响的体外评估。本品仅用于科研,不用于临床诊断,产品具体参数及操作步骤详见产品说明书。
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缩写:APOA4
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Uniprot No.:
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种属:Homo sapiens (Human)
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样本类型:serum, plasma, tissue homogenates
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检测范围:0.041 ng/ml- 30 ng/ml
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灵敏度:0.041 ng/ml
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反应时间:1-5h
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样本体积:50-100ul
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检测波长:450 nm
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研究领域:Cancer
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测定原理:quantitative
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测定方法:Sandwich
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精密度:
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线性度:
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回收率:
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标准曲线:
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数据处理:
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货期:3-5 working days
引用文献
- Depression Augments Plasma APOA4 without Changes of Plasma Lipids and Glucose in Female Adolescents Carrying G Allele of APOA4 rs5104 QW Guo,Journal of Molecular Neuroscience,2021
- Screening and identification of potential protein biomarkers for evaluating the efficacy of intensive therapy in pulmonary tuberculosis Ting-TingJiang.et al,Biochemical and Biophysical Research Communications,2018
靶点详情
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最新研究进展:APOA4是一种主要存在于高密度脂蛋白(HDL)中的蛋白质。最新研究表明,APOA4在人体内具有抗炎、抗氧化、调节脂质代谢和血糖代谢等多种生物学功能。APOA4的异常表达与多种代谢性疾病,如肥胖、2型糖尿病和心血管疾病等的发生密切相关。
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功能:May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons.
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亚细胞定位:Secreted.
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蛋白家族:Apolipoprotein A1/A4/E family
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组织特异性:Synthesized primarily in the intestine and secreted in plasma.
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数据库链接:
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