Your Good Partner in Biology Research

中文简体

CSF2｜ CTLA4｜ DLL3｜ EGFR｜ IL4｜ IL4R｜ LAG3｜ MSTN｜ NECTIN4｜ NT5E｜ SEZ6｜ TM4SF1｜ TNFSF13｜ TPO

  1. 首页
  2. 试剂盒
  3. 酶联免疫试剂盒
  4. Human Angiopoietin-related protein 7(ANGPTL7) ELISA kit

Human Angiopoietin-related protein 7(ANGPTL7) ELISA kit

文献引用 (2) 说明书下载
  • 中文名称：
    人血管生成素相关蛋白7(ANGPTL7)酶联免疫试剂盒
  • 货号：
    CSB-EL001715HU
  • 规格：
    96T/48T
  • 价格：
    ￥3600/￥2500
  • 其他：
CUSABIO Wins 2024 Bioz Rapid Star™ Award in the ELISA category

产品详情

  • 产品描述：
    人血管生成素相关蛋白7(ANGPTL7)酶联免疫试剂盒（CSB-EL001715HU）为双抗夹心法ELISA试剂盒，定量检测血清、血浆、组织匀浆样本中的ANGPTL7含量。ANGPTL7是一种血管生成素样蛋白，参与血管生成、炎症反应、内皮细胞损伤和糖脂代谢。研究发现，ANGPTL7在阻塞性睡眠呼吸暂停低通气综合征（OSAHS）患者中表达升高，可能与OSAHS的发生发展相关，并通过调节炎症反应、内皮损伤和脂代谢等机制影响疾病进程。试剂盒检测范围为0.312 ng/mL-20 ng/mL，该产品适用于基础医学研究中ANGPTL7在血管发育、代谢调控及病理状态下的动态变化分析，也可用于药物筛选模型中靶向干预效果的评估，为眼科疾病机制探索、代谢相关研究及生物标志物开发提供高效检测方案。本品仅用于科研，不用于临床诊断，产品具体参数及操作步骤详见产品说明书。
  • 别名：
    Angiopoietin like 7 ELISA Kit; Angiopoietin like factor (CDT6) ELISA Kit; Angiopoietin like factor ELISA Kit; Angiopoietin related protein 7 ELISA Kit; Angiopoietin-like factor ELISA Kit; Angiopoietin-like protein 7 ELISA Kit; Angiopoietin-related protein 7 ELISA Kit; ANGL7_HUMAN ELISA Kit; ANGPTL7 ELISA Kit; AngX ELISA Kit; CDT6 ELISA Kit; Cornea derived transcript 6 protein ELISA Kit; Cornea-derived transcript 6 protein ELISA Kit; dJ647M16.1 ELISA Kit; OTTHUMP00000001986 ELISA Kit; RP4-647M16.2 ELISA Kit
  • 缩写：
    ANGPTL7
  • Uniprot No.：
  • 种属：
    Homo sapiens (Human)
  • 样本类型：
    serum, plasma, tissue homogenates
  • 检测范围：
    0.312 ng/mL-20 ng/mL
  • 灵敏度：
    0.078 ng/mL
  • 反应时间：
    1-5h
  • 样本体积：
    50-100ul
  • 检测波长：
    450 nm
  • 研究领域：
    Neuroscience
  • 测定原理：
    quantitative
  • 测定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 线性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of human ANGPTL7 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
    　 Sample Serum(n=4)
    1:1 Average % 99
    Range % 92-104
    1:2 Average % 87
    Range % 82-93
    1:4 Average % 92
    Range % 87-98
    1:8 Average % 101
    Range % 98-105
  • 回收率：
    The recovery of human ANGPTL7 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample Type Average % Recovery Range
    Serum (n=5) 103 92-106
    EDTA plasma (n=4) 95 89-99
  • 标准曲线：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    ng/ml OD1 OD2 Average Corrected
    20 1.942 2.042 1.992 1.881
    10 1.239 1.149 1.194 1.083
    5 0.759 0.719 0.739 0.628
    2.5 0.453 0.464 0.459 0.348
    1.25 0.311 0.321 0.316 0.205
    0.625 0.212 0.223 0.218 0.107
    0.312 0.161 0.165 0.163 0.052
    0 0.110 0.111 0.111 　
  • 数据处理：
    ELISA操作视频及标曲绘制软件下载
  • 货期：
    3-5 working days

引用文献

产品评价

相关产品

ANGPTL7 antibodies

ANGPTL7 Proteins

靶点详情

  • 功能：
    Has a role in the formation and organization of the extracellular matrix. In the eye, it functions as a mediator of dexamethasone-induced matrix deposition in the trabecular meshwork, the tissue responsible for the outflow of the ocular aqueous humor and for the maintenance of intraocular pressure. Is a negative regulator of angiogenesis in the cornea, and plays a major role in maintaining corneal avascularity and transparency.
  • 基因功能参考文献：
    1. obesity increases the level of ANGPTL7 in both plasma and adipose tissue. Increased expression of ANGPTL7 might play a minor role in the regulation of TG level in obese subjects either directly or through interaction with other ANGPTL protein members. Physical exercise reduced the level of ANGPTL7 highlighting the potential for targeting this protein as a therapeutic target for regulating dyslipidemia. PMID: 28264047
    2. ANGPTL7, which is abundantly expressed in keratocytes, plays a major role in maintaining corneal avascularity and transparency. PMID: 25622036
    3. ANGPTL7 is markedly down regulated in metastatic liver cancer. PMID: 25854806
    4. Angiopoietin-like 7 is a novel pro-angiogenetic factor over-expressed in cancer PMID: 24903490
    5. Together with previous findings, these properties strengthen ANGPTL7's candidacy for the regulation of intraocular pressure and glaucoma. PMID: 21199193
    6. Induction of ANGPTL7 secretion by glaucoma stimuli and increased concentration of ANGPTL7 in glaucomatous AH suggest that ANGPTL7 is overexpressed in glaucoma. PMID: 18421092

    显示更多

    收起更多

  • 亚细胞定位：
    Secreted.
  • 组织特异性：
    Higly expressed in the cornea (at protein level). Expression is restricted to the stromal layer. Also detected at the junction between the corneal stromal layer and the conjuctiva. Not detected in the sclera.
  • 数据库链接：

    HGNC: 24078

    KEGG: hsa:10218

    STRING: 9606.ENSP00000366015

    UniGene: Hs.146559

Most popular with customers

产品中心
特别关注


X
九游平台-九游(中国) | 米兰体育-米兰体育（中国） | 开云手机在线登陆入口 | 江南官方体育网页版 | 开云网页版 | 开云官方在线入口 | 开云电子体育 | 开云官方链接 | 江南网页版页面登录 |
九游平台-九游(中国) | 米兰体育-米兰体育（中国） | 开云手机在线登陆入口 | 江南官方体育网页版 | 开云网页版 | 开云官方在线入口 | 开云电子体育 | 开云官方链接 | 江南网页版页面登录 |