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Horse Interleukin 8,IL-8 ELISA Kit

  • 中文名称:
    马白介素8(IL-8/CXCL8)酶联免疫试剂盒
  • 货号:
    CSB-E14021Hs
  • 规格:
    96T/48T
  • 价格:
    ¥3800/¥2500
  • 其他:

产品详情

  • 产品描述:
    CUSABIO人白介素8(IL-8/CXCL8)定量检测ELISA试剂盒(货号:CSB-E14021Hs),采用双抗体夹心法原理,可精准检测血清、血浆及组织匀浆样本中IL-8的蛋白表达水平。IL-8是一种重要的趋化因子,在炎症反应、免疫调控及肿瘤微环境建立中发挥关键作用,其动态变化常作为炎症性疾病、感染性疾病及癌症机制研究的生物标志物。试剂盒检测线性范围为15.6-1000 pg/mL,具备高特异性和稳定性,适用于细胞因子网络研究、药物作用机制探索、疾病模型评估等科研领域,可兼容常规实验室操作流程,为体外实验、动物模型或临床前研究提供可靠的IL-8浓度检测方案。实验过程包含预包被捕获抗体、生物素标记检测抗体及链霉亲和素-HRP系统,通过标准曲线实现目标蛋白的准确定量分析。
  • 别名:
    CXCL8 ELISA Kit; IL8 ELISA Kit; Interleukin-8 ELISA Kit; IL-8 ELISA Kit; C-X-C motif chemokine 8 ELISA Kit; Chemokine ELISA Kit; C-X-C motif) ligand 8 ELISA Kit
  • 缩写:
  • Uniprot No.:
  • 种属:
    Equus caballus (Horse)
  • 样本类型:
    serum, plasma, tissue homogenates
  • 检测范围:
    15.6 pg/mL-1000 pg/mL
  • 灵敏度:
    3.9 pg/mL
  • 反应时间:
    1-5h
  • 样本体积:
    50-100ul
  • 检测波长:
    450 nm
  • 研究领域:
    Immunology
  • 测定原理:
    quantitative
  • 测定方法:
    Sandwich
  • 数据处理:
  • 货期:
    3-5 working days

引用文献

产品评价

靶点详情

  • 功能:
    IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus.
  • 基因功能参考文献:
    1. Results suggested that chemokine expression by cultured equine BECs following exposure to pulmonary hemorrhage conditions may contribute to the development of inflammatory airway disease in horses. PMID: 22280393
    2. Mapped six genes (EIF4G3, HSP90, RBBP6, IL8, TERT, and TERC) on the chromosomes of Equus caballus, Equus asinus, Equus grevyi, and Equus burchelli by fluorescence in situ hybridization. PMID: 21774619
    3. This study examined effects of in vitro exposure to solutions of hay dust, lipopolysaccharides, or beta-glucan on cytokine expression in pulmonary mononuclear cells isolated from healthy horses and horses with recurrent airway obstruction. PMID: 18052742
    4. These results suggest that MMP-1 and IL-8 are both involved in the exercise-induced stress response, and this represents a starting point from which to understand the adaptive responses to this phenomenon. PMID: 19552796
    5. The acute pulmonary neutrophilia characteristic of recurrent airway obstruction was not associated with an increase in expression of chemokines in pulmonary mononuclear cells from disease-susceptible horses. PMID: 19795943

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  • 亚细胞定位:
    Secreted.
  • 蛋白家族:
    Intercrine alpha (chemokine CxC) family
  • 数据库链接: