Horse Interleukin 8,IL-8 ELISA Kit
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中文名称:马白介素8(IL-8/CXCL8)酶联免疫试剂盒
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货号:CSB-E14021Hs
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规格:96T/48T
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价格:¥3800/¥2500
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其他:
产品详情
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产品描述:CUSABIO人白介素8(IL-8/CXCL8)定量检测ELISA试剂盒(货号:CSB-E14021Hs),采用双抗体夹心法原理,可精准检测血清、血浆及组织匀浆样本中IL-8的蛋白表达水平。IL-8是一种重要的趋化因子,在炎症反应、免疫调控及肿瘤微环境建立中发挥关键作用,其动态变化常作为炎症性疾病、感染性疾病及癌症机制研究的生物标志物。试剂盒检测线性范围为15.6-1000 pg/mL,具备高特异性和稳定性,适用于细胞因子网络研究、药物作用机制探索、疾病模型评估等科研领域,可兼容常规实验室操作流程,为体外实验、动物模型或临床前研究提供可靠的IL-8浓度检测方案。实验过程包含预包被捕获抗体、生物素标记检测抗体及链霉亲和素-HRP系统,通过标准曲线实现目标蛋白的准确定量分析。
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别名:CXCL8 ELISA Kit; IL8 ELISA Kit; Interleukin-8 ELISA Kit; IL-8 ELISA Kit; C-X-C motif chemokine 8 ELISA Kit; Chemokine ELISA Kit; C-X-C motif) ligand 8 ELISA Kit
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缩写:
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Uniprot No.:
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种属:Equus caballus (Horse)
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样本类型:serum, plasma, tissue homogenates
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检测范围:15.6 pg/mL-1000 pg/mL
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灵敏度:3.9 pg/mL
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反应时间:1-5h
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样本体积:50-100ul
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检测波长:450 nm
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研究领域:Immunology
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测定原理:quantitative
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测定方法:Sandwich
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数据处理:
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货期:3-5 working days
引用文献
- Does antimicrobial therapy improve outcomes in horses with severe equine asthma and a positive tracheal wash bacterial culture? Husulak, Michelle L.et al,Canadian Journal of Veterinary Research,2018
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靶点详情
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功能:IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus.
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基因功能参考文献:
- Results suggested that chemokine expression by cultured equine BECs following exposure to pulmonary hemorrhage conditions may contribute to the development of inflammatory airway disease in horses. PMID: 22280393
- Mapped six genes (EIF4G3, HSP90, RBBP6, IL8, TERT, and TERC) on the chromosomes of Equus caballus, Equus asinus, Equus grevyi, and Equus burchelli by fluorescence in situ hybridization. PMID: 21774619
- This study examined effects of in vitro exposure to solutions of hay dust, lipopolysaccharides, or beta-glucan on cytokine expression in pulmonary mononuclear cells isolated from healthy horses and horses with recurrent airway obstruction. PMID: 18052742
- These results suggest that MMP-1 and IL-8 are both involved in the exercise-induced stress response, and this represents a starting point from which to understand the adaptive responses to this phenomenon. PMID: 19552796
- The acute pulmonary neutrophilia characteristic of recurrent airway obstruction was not associated with an increase in expression of chemokines in pulmonary mononuclear cells from disease-susceptible horses. PMID: 19795943
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亚细胞定位:Secreted.
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蛋白家族:Intercrine alpha (chemokine CxC) family
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数据库链接:
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