Bovine Interferon β,IFN-β/IFNB ELISA Kit
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中文名称：牛β干扰素(IFN-β/IFNB)酶联免疫试剂盒
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货号：CSB-E13699B
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规格：96T/48T
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价格：￥4200/￥3000
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其他：
产品详情
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产品描述：CUSABIO试剂盒采用竞争法酶联免疫吸附原理，专为定量检测牛β干扰素（IFN-β/IFNB）设计，其检测体系基于生物素-链霉亲和素放大系统，可灵敏识别样本中的目标蛋白。牛IFN-β作为I型干扰素家族重要成员，在抗病毒免疫应答中发挥核心作用，通过激活JAK-STAT信号通路诱导数百种干扰素刺激基因表达，在病毒感染模型、免疫调节机制等研究中具有重要价值。该试剂盒适用于血清、血浆或细胞培养上清等生物样本分析，检测流程约3.5小时完成，包含预包被抗体、标准品及显色底物等核心组分，标准曲线范围覆盖15.6-1000 pg/mL，满足低丰度样本检测需求。科研人员可将其应用于畜牧病原体感染模型评估、疫苗免疫效力研究或抗病毒药物筛选等领域，为探究宿主防御机制及疾病防控策略提供可靠工具。试剂盒在出厂前经过严格质控，批内重复性优异，建议实验时配合牛种属特异性样本预处理方案以保障检测准确性。
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别名：IFNB1Interferon beta-1 ELISA Kit
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缩写：
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Uniprot No.：
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种属：Bos taurus (Bovine)
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样本类型：
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检测范围：
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灵敏度：
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反应时间：1-5h
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样本体积：50-100ul
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检测波长：450 nm
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研究领域：Immunology
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测定原理：quantitative
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测定方法：Competitive
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精密度：
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线性度：
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回收率：
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标准曲线：
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数据处理：
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货期：3-5 working days
引用文献
- MiR-103/miR-107 inhibits enterovirus 71 replication and facilitates type I interferon response by regulating SOCS3/STAT3 pathway B Huan,Biotechnology Letters,2021
- Attenuated Mycoplasma bovis strains provide protection against virulent infection in calves. Zhang R et al,Vaccine,2014
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靶点详情
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功能：Has antiviral, antibacterial and anticancer activities.
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基因功能参考文献：
- BVDV2-E significantly increased IFN-beta activity compared to BVDV2-wt. PMID: 28432927
- The data confirm the involvement of EHMT2 in the epigenetic regulation of IFN-b and demonstrate the activation of a general antiviral state after EHMT2 inhibition. PMID: 26418342
- The authors provide evidence that ICP27 protein encoded by bovine herpesvirus type 1, a viral early protein that shuttles between the nucleus and cytoplasm inhibits transcriptional activity of two bovine IFN-beta gene promoters (IFN-beta1 and IFN-beta3). PMID: 22902481
- The authors demonstrate that bovine herpesvirus 1 bICP0 effectively inhibits bovine IFN-beta promoter activity and induces IRF3 degradation. PMID: 21689696
- These studies provide evidence that virus infection differentially stimulates expression of the three bovine IFN-beta genes. PMID: 21316405
- recombinant bovine respiratory syncytial virus lacking the NS proteins, and those lacking NS2 in particular, are strong inducers of IFN-alpha/beta in bovine nasal fibroblasts and bronchoalveolar macrophages. PMID: 12857912
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亚细胞定位：Secreted.
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蛋白家族：Alpha/beta interferon family
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数据库链接：
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