RPL6 Antibody

产品详情

Uniprot No.：

Q02878
基因名：

RPL6
别名：

60S ribosomal protein L6 antibody; DNA-binding protein TAXREB107 antibody; L6 antibody; Neoplasm-related protein C140 antibody; Ribosomal protein L6 antibody; RL6_HUMAN antibody; rpl6 antibody; SHUJUN-2 antibody; TAX-responsive enhancer element-binding protein 107 antibody; TAXREB107 antibody; TXREB1 antibody
宿主：

Rabbit
反应种属：

Human,Mouse,Rat
免疫原：

Human RPL6
免疫原种属：

Homo sapiens (Human)
抗体亚型：

IgG
纯化方式：

Antigen Affinity purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
产品提供形式：

Liquid
应用范围：

ELISA,WB,IHC
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Component of the large ribosomal subunit.; (Microbial infection) Specifically binds to domain C of the Tax-responsive enhancer element in the long terminal repeat of HTLV-I.
基因功能参考文献：
1. The ribosomal protein L6 binds to and suppresses the E3 ubiquitin ligase activity of HDM2, and subsequently attenuates HDM2-mediated p53 polyubiquitination and degradation. PMID: 24174547
2. Down-regulation of RPL6 could suppress cell growth and cell cycle progression at least through down-regulating cyclin E PMID: 22043320
3. RPL6 was overexpressed in human gastric cancer and its over-expression could promote cell growth and cell cycle progression at least through upregulating cyclin E expression. PMID: 20171175
4. The high expression of RPL6/Taxreb107 in drug resistant gastric cancer cell shows its correlation with multiple-drug resistance in gastric cancer. PMID: 12678981
亚细胞定位：

Cytoplasm, cytosol. Cytoplasm. Rough endoplasmic reticulum.
蛋白家族：

Eukaryotic ribosomal protein eL6 family
数据库链接：

HGNC: 10362

OMIM: 603703

KEGG: hsa:6128

STRING: 9606.ENSP00000202773

UniGene: Hs.528668