DEPP1 Antibody, Biotin conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) DEPP1 Polyclonal antibody
Uniprot No.：

Q9NTK1
基因名：

DEPP1
别名：

Decidual protein induced by progesterone antibody; Depp antibody; DEPP_HUMAN antibody; Fasting-induced gene protein antibody; FIG antibody; Protein DEPP antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Protein DEPP1 protein (57-174AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

Biotin
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Acts as a critical modulator of FOXO3-induced autophagy via increased cellular ROS.
基因功能参考文献：
1. Knockdown of DEPP prevented the primary and secondary reactive oxygen species wave during FOXO3 activation. PMID: 25261981
2. C10orf10 expression is frequently decreased in breast cancer tissues and is associated with shorter survival times. PMID: 24936657
3. DEPP is regulated at the level of transcription by FoxO in human vascular endothelial cells PMID: 21510935
4. DEPP is a novel insulin-regulatory molecule expressed abundantly in insulin-sensitive tissues including white adipose tissue and liver. PMID: 19937567
5. Expressed in endothelial cells of peripheral tissues, but not in atrial or ventricular endocardial cells of the heart, unexpected degree of molecular heterogeneity among arterial endothelial cells, up-regulated in subsets of endothelial cells. PMID: 15977181
6. Depp modulates the effects of progesterone during decidualization and in the decidua by affecting gene expression. PMID: 16123073
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亚细胞定位：

Cytoplasm. Peroxisome. Mitochondrion.
组织特异性：

Expressed in various tissues, including pancreas, placenta, ovary, testis and kidney.
数据库链接：

HGNC: 23355

OMIM: 611309

KEGG: hsa:11067

STRING: 9606.ENSP00000298295

UniGene: Hs.93675